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  1. Chromosome 22q11.2 deletion syndrome is one of the most common genetic causes of cognitive impairment and developmental disability yet little is known about the neural bases of those challenges. Here we expand...

    Authors: Tony J Simon, Zhongle Wu, Brian Avants, Hui Zhang, James C Gee and Glenn T Stebbins

    Citation: Behavioral and Brain Functions 2008 4:25

    Content type: Research

    Published on:

  2. NS2359 is a potent reuptake blocker of noradrenalin, dopamine, and serotonin. The aim of the study was to investigate the efficacy, safety and cognitive function of NS2359 in adults with a DSM IV diagnosis of ...

    Authors: Timothy E Wilens, Thorsten Klint, Lenard Adler, Scott West, Keith Wesnes, Ole Graff and Birgit Mikkelsen

    Citation: Behavioral and Brain Functions 2008 4:24

    Content type: Research

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  3. This study posed the question whether strain differences in stress-reactivity lead to differential behavioral responses in two different tests of anxiety. Strain differences in anxiety-measures are known, but ...

    Authors: Katarzyna Nosek, Kristen Dennis, Brian M Andrus, Nasim Ahmadiyeh, Amber E Baum, Leah C Solberg Woods and Eva E Redei

    Citation: Behavioral and Brain Functions 2008 4:23

    Content type: Research

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  4. We study the voltage dependent calcium channels and nitric oxide involvement in angiotensin II-induced pressor effect. The antipressor action of L-Type calcium channel antagonist, nifedipine, has been studied ...

    Authors: Wilson A Saad, Ismael FMS Guarda, Luiz AA Camargo and Talmir AFB Santos

    Citation: Behavioral and Brain Functions 2008 4:22

    Content type: Research

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  5. Monoamine oxidase A (MAOA) is a mitochondrial enzyme involved in degrading several different biological amines, including serotonin. Although several pieces of evidence suggested that MAOA is important in the ...

    Authors: Yi-Mei J Lin, Fabian Davamani, Wei-Chih Yang, Te-Jen Lai and H Sunny Sun

    Citation: Behavioral and Brain Functions 2008 4:21

    Content type: Research

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  7. A number of neurophysiological characteristics demonstrated in autism share the common theme of under-connectivity in the cerebral cortex. One of the prominent theories of the cause of the dysfunctional connec...

    Authors: Mark Tommerdahl, Vinay Tannan, Jameson K Holden and Grace T Baranek

    Citation: Behavioral and Brain Functions 2008 4:19

    Content type: Research

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  8. This study was realized thanks to the collaboration of children and adolescents who had been resected from cerebellar tumors. The medulloblastoma group (CE+, n = 7) in addition to surgery received radiation an...

    Authors: Encarna Vaquero, Carlos M. Gómez, Eliana A. Quintero, Javier J. González-Rosa and Javier Márquez

    Citation: Behavioral and Brain Functions 2008 4:18

    Content type: Research

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  10. While low-grade inflammation has consistently been observed in subjects with depression, studies on the possible relationship between inflammation and other aspects of brain function are as yet sparse. In this...

    Authors: Susanne Henningsson, Fariba Baghaei, Roland Rosmond, Göran Holm, Mikael Landén, Henrik Anckarsäter and Agneta Ekman

    Citation: Behavioral and Brain Functions 2008 4:16

    Content type: Research

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  13. The Somatic Marker Hypothesis suggests that normal subjects are "foreseeable" and ventromedial prefrontal patients are "myopic" in making decisions, as the behavior shown in the Iowa Gambling Task. The present...

    Authors: Yao-Chu Chiu, Ching-Hung Lin, Jong-Tsun Huang, Shuyeu Lin, Po-Lei Lee and Jen-Chuen Hsieh

    Citation: Behavioral and Brain Functions 2008 4:13

    Content type: Short paper

    Published on:

  15. Autism Spectrum Conditions (ASCs) are characterized by a high degree of clinical heterogeneity, but the extent to which this variation represents a severity gradient versus discrete phenotypes is unclear. This...

    Authors: Howard Ring, Marc Woodbury-Smith, Peter Watson, Sally Wheelwright and Simon Baron-Cohen

    Citation: Behavioral and Brain Functions 2008 4:11

    Content type: Research

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  16. Chromosome aberrations have long been studied in an effort to identify susceptibility genes for schizophrenia. Chromosome 22q11.2 microdeletion is associated with DiGeorge and Velocardiofacial syndromes (DG/VC...

    Authors: Anna Brunet, Lluís Armengol, Trini Pelaez, Roser Guillamat, Vicenç Vallès, Elisabeth Gabau, Xavier Estivill and Miriam Guitart

    Citation: Behavioral and Brain Functions 2008 4:10

    Content type: Short paper

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  18. Attention-Deficit/Hyperactivity Disorder (ADHD) is a prevalent, complex disorder which is characterized by symptoms of inattention, hyperactivity, and impulsivity. Convergent evidence from neurobiological stud...

    Authors: Colleen Dockstader, William Gaetz, Douglas Cheyne, Frank Wang, F Xavier Castellanos and Rosemary Tannock

    Citation: Behavioral and Brain Functions 2008 4:8

    Content type: Research

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  19. The inability to inhibit reinforced responses is a defining feature of ADHD associated with impulsivity. The Spontaneously Hypertensive Rat (SHR) has been extolled as an animal model of ADHD, but there is no c...

    Authors: Federico Sanabria and Peter R Killeen

    Citation: Behavioral and Brain Functions 2008 4:7

    Content type: Research

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  22. It has been hypothesized that genetic and environmental factors relate to psychiatric disorders through the effect of intermediating, vulnerability traits called endophenotypes. The study had a threefold aim: ...

    Authors: Nanda NJ Rommelse, Marieke E Altink, Neilson C Martin, Cathelijne JM Buschgens, Stephen V Faraone, Jan K Buitelaar, Joseph A Sergeant and Jaap Oosterlaan

    Citation: Behavioral and Brain Functions 2008 4:4

    Content type: Research

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  23. ADHD is currently defined as a cognitive/behavioral developmental disorder where all clinical criteria are behavioral. Overactivity, impulsiveness, and inattentiveness are presently regarded as the main clinic...

    Authors: Terje Sagvolden and Tong Xu

    Citation: Behavioral and Brain Functions 2008 4:3

    Content type: Research

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  24. Calcineurin is a neuron-enriched phosphatase that regulates synaptic plasticity and neuronal adaptation. Activation of calcineurin, overall, antagonizes the effects of the cyclic AMP activated protein/kinase A...

    Authors: Flavie Mathieu, Stéphanie Miot, Bruno Etain, Marie-Anne El Khoury, Fabien Chevalier, Frank Bellivier, Marion Leboyer, Bruno Giros and Eleni T Tzavara

    Citation: Behavioral and Brain Functions 2008 4:2

    Content type: Short paper

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  25. Cocaine addiction involves a number of medical, psychological and social problems. Understanding the genetic aetiology of this disorder will be essential for design of effective treatments. Dopamine-beta hydro...

    Authors: Camila Guindalini, Ronaldo Laranjeira, David Collier, Guilherme Messas, Homero Vallada and Gerome Breen

    Citation: Behavioral and Brain Functions 2008 4:1

    Content type: Short paper

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  26. Recent cognitive and computational models (e.g. the Interacting Neighbors Model) state that in simple multiplication decade and unit digits of the candidate answers (including the correct result) are represent...

    Authors: Frank Domahs, Ulrike Domahs, Matthias Schlesewsky, Elie Ratinckx, Tom Verguts, Klaus Willmes and Hans-Christoph Nuerk

    Citation: Behavioral and Brain Functions 2007 3:66

    Content type: Research

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  27. Misassigned alleles can annihilate efforts to control quality in otherwise well-designed genetic association analyses. To date, the issue remains underreported, as is exemplified by studies of a diallelic DRD2 mi...

    Authors: Philipp G Sand

    Citation: Behavioral and Brain Functions 2007 3:65

    Content type: Commentary

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  28. The dopamine-derived tetrahydroisoquinolines (TIQ) synthesized endogeneously from aldehydes and catecholamines have shown to modulate neurotransmission, central metabolism and motor activity. Converging eviden...

    Authors: Veit Roessner, Susanne Walitza, Franz Riederer, Regina Hünnerkopf, Aribert Rothenberger, Manfred Gerlach and Andreas Moser

    Citation: Behavioral and Brain Functions 2007 3:64

    Content type: Research

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  29. Speech perception is based on a variety of spectral and temporal acoustic features available in the acoustic signal. Voice-onset time (VOT) is considered an important cue that is cardinal for phonetic perception.

    Authors: Tino Zaehle, Lutz Jancke and Martin Meyer

    Citation: Behavioral and Brain Functions 2007 3:63

    Content type: Research

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  30. It has been acknowledged that the frequency spectrum of measured electromagnetic (EM) brain signals shows a decrease in power with increasing frequency. This spectral behaviour may lead to difficulty in distin...

    Authors: Charmaine Demanuele, Christopher J James and Edmund JS Sonuga-Barke

    Citation: Behavioral and Brain Functions 2007 3:62

    Content type: Research

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  31. A subject's ability to differentiate the loci of two points on the skin depends on the stimulus-evoked pericolumnar lateral inhibitory interactions which increase the spatial contrast between regions of SI cor...

    Authors: Mark Tommerdahl, Vinay Tannan, Matt Zachek, Jameson K Holden and Oleg V Favorov

    Citation: Behavioral and Brain Functions 2007 3:61

    Content type: Research

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  32. Attention-deficit/hyperactivity disorder (ADHD) is characterized by a pattern of inattention, hyperactivity, and impulsivity that is cross-situational, persistent, and produces social and academic impairment. ...

    Authors: Espen B Johansen, Peter R Killeen and Terje Sagvolden

    Citation: Behavioral and Brain Functions 2007 3:60

    Content type: Research

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  33. Individuals with social phobia are more likely to misinterpret ambiguous social situations as more threatening, i.e. they show an interpretive bias. This study investigated whether such a bias also exists in s...

    Authors: Iris-Tatjana Kolassa, Arlette Buchmann, Romy Lauche, Stephan Kolassa, Ivailo Partchev, Wolfgang HR Miltner and Frauke Musial

    Citation: Behavioral and Brain Functions 2007 3:59

    Content type: Research

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  34. The mitogen-activated protein kinases, MAPKs for short, constitute cascades of signalling pathways involved in the regulation of several cellular processes that include cell proliferation, differentiation and ...

    Authors: Nancy Gerits, Werner Van Belle and Ugo Moens

    Citation: Behavioral and Brain Functions 2007 3:58

    Content type: Research

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  35. We examined the hypothesis that deficits in learning, memory, and other cognitive functions are associated with the ε4 allele of the Apolipoprotein E (APOE) gene in a non-demented sample with memory complaints...

    Authors: Eike Wehling, Astri J Lundervold, Brit Standnes, Leif Gjerstad and Ivar Reinvang

    Citation: Behavioral and Brain Functions 2007 3:57

    Content type: Research

    Published on:

  36. Dorsolateral prefrontal cortex (DLPFC), posterior parietal cortex, and regions in the occipital cortex have been identified as neural sites for visual working memory (WM). The exact involvement of the DLPFC in ve...

    Authors: Christoph Rothmayr, Oliver Baumann, Tor Endestad, Roland M Rutschmann, Svein Magnussen and Mark W Greenlee

    Citation: Behavioral and Brain Functions 2007 3:56

    Content type: Research

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  38. Previous investigations of individuals with chromosome 22q11.2 deletion syndrome (DS22q11.2) have reported alterations in both brain anatomy and cognitive function. Neuroanatomical studies have reported multip...

    Authors: Tracy DeBoer, Zhongle Wu, Aaron Lee and Tony J Simon

    Citation: Behavioral and Brain Functions 2007 3:54

    Content type: Research

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  41. Recent advances have led to an understanding that the hippocampus is involved more broadly than explicit or declarative memory alone. Tasks which involve the acquisition of complex associations involve the hip...

    Authors: Anthony J Greene

    Citation: Behavioral and Brain Functions 2007 3:51

    Content type: Commentary

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  42. Previous linkage and association studies may have implicated the Dystrobrevin-binding protein 1 (DTNBP1) gene locus or a gene in linkage disequilibrium with DTNBP1 on chromosome 6p22.3 in genetic susceptibilit...

    Authors: Susmita R Datta, Andrew McQuillin, Vinay Puri, Khalid Choudhury, Srinivasa Thirumalai, Jacob Lawrence, Jonathan Pimm, Nicholas Bass, Graham Lamb, Helen Moorey, Jenny Morgan, Bhaskar Punukollu, Gomathinayagam Kandasami, Simon Kirwin, Akeem Sule, Digby Quested…

    Citation: Behavioral and Brain Functions 2007 3:50

    Content type: Short paper

    Published on:

  43. Management of pain involves a balance between inhibition of pain and minimization of side effects; therefore, in developing new analgesic compounds, one must consider the effects of treatment on both pain proc...

    Authors: John K Neubert, Heather L Rossi, Jonathan Pogar, Alan C Jenkins and Robert M Caudle

    Citation: Behavioral and Brain Functions 2007 3:49

    Content type: Research

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  45. Since a genetic disposition for depression is probable, there ought to be biochemical changes. Increased peptide levels with relevant bioactivities have been found in urine in a previous investigation, which m...

    Authors: Ying Liu, Tore Heiberg and Karl-Ludvig Reichelt

    Citation: Behavioral and Brain Functions 2007 3:47

    Content type: Research

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  46. Several linkage studies across multiple population groups provide convergent support for susceptibility loci for schizophrenia – and, more recently, for affective disorder – on chromosome 6q. We explore whethe...

    Authors: Zuowei Wang, Yiru Fang, Shunying Yu, Chengmei Yuan, Wu Hong, Zhenghui Yi, Sanduo Jiang, R Kelsoe John and Zucheng Wang

    Citation: Behavioral and Brain Functions 2007 3:46

    Content type: Research

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  47. Three experiments studied the hedonicity of decision making. Participants rated their pleasure/displeasure while reading item-sentences describing political and social problems followed by different decisions ...

    Authors: Michel Cabanac and Marie-Claude Bonniot-Cabanac

    Citation: Behavioral and Brain Functions 2007 3:45

    Content type: Research

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  48. Many human neuroimaging investigations on recognition memory employ verbal instructions to direct subject's attention to a stimulus attribute. But do the same or a similar neurophysiological process occur duri...

    Authors: Michael W Schlund and Michael F Cataldo

    Citation: Behavioral and Brain Functions 2007 3:44

    Content type: Research

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  49. It is known that the orthographic properties of linguistic stimuli are processed within the left occipitotemporal cortex at about 150–200 ms. We recorded event-related potentials (ERPs) to words in standard or...

    Authors: Alice M Proverbio, Friederike Wiedemann, Roberta Adorni, Valentina Rossi, Marzia Del Zotto and Alberto Zani

    Citation: Behavioral and Brain Functions 2007 3:43

    Content type: Research

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  50. Contemporary neuropsychological models of ADHD implicate impaired cognitive control as contributing to disorder characteristic behavioral deficiencies and excesses; albeit to varying degrees. While the traditi...

    Authors: Joseph A King, Michael Colla, Marcel Brass, Isabella Heuser and DY von Cramon

    Citation: Behavioral and Brain Functions 2007 3:42

    Content type: Research

    Published on:

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Behavioral and Brain Functions

ISSN: 1744-9081

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